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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG$ S( U! k% W0 n3 d8 ^; Y
如果是中国长大的,英语能到这种程度真是很不简单。0 x. p0 D8 V* t C5 B+ [
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania0 n8 m. A% e: Z0 c0 {
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It is a shame to see Nature — which nearly all scientists, including myself
) }3 u( U3 G& B) a, regard as one of the most prestigious and influential physical-science- t/ P+ ~+ N2 ^* ?# f2 |- z
magazines — publish a thinly veiled biased article like this. Granted, this d4 k/ @2 Q% a1 ^
is not a peer-reviewed scientific article and did not go through the
1 w. D; w# j: }: Q% W. h- lscrutiny of picking referees. But to serve as a channel for the general
+ r( s! K, b' {, |/ Bpopulace to be in touch with and appreciate science, the authors and editors$ u8 z2 s) J2 x" J
should at least present the readers with facts within the proper context,2 O8 s& E# D) w
which they blatantly failed to do.
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+ h' w& r1 E0 {- L, [First, to identify Ye’s performance increase, Ewen Callaway compared her, G- R; ~* O8 Q+ \5 G% t. i8 h
Olympic 400-metre IM time with her performance at the World Championships in
4 Y9 z; m" l# T6 T' ~6 ^4 Z" ?3 I2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
# X2 E0 w, i, Q7 V( b/ }8 X* [! ianomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
; w$ `; h- J& C, m/ Bpersonal best was 4:33.79 at the Asian Games in 2010. This leads to an
! [. M1 v$ P( s/ u, U2 ?; |improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
: I+ G$ R3 H6 O: X% y% ldifference between the gold and silver medal, I see no reason for 5.38 s to
2 |5 T# j# S3 Z( O9 _! b4 O" f2 Ibe treated as 7 s.8 z8 I& W q: J
0 | m- _- V( d/ A* ESecond, as previously pointed out, Ye is only 16 years old and her body is5 g- K9 O8 f$ `
still developing. Bettering oneself by 5 seconds over two years may seem
2 x9 D0 e; I, o; l/ Zimpossible for an adult swimmer, but it certainly happens among youngsters.! d. T3 k2 h6 c5 p! d" W
An interview with Australian gold medallist Ian Thorpe revealed that his 400
3 N& b* v9 X5 ]6 O# n+ P-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
& ?5 `: w X( N! n: `3 e+ CFor regular people, including Callaway, it may be hard to imagine what an- g& }+ e, m" x! o
elite swimmer can achieve as he or she matures and undergoes scientific and' E; K! g+ X. m7 V! ^
persistent training. But jumping to the conclusion that it is “anomalous”+ I+ t' O ~( X% H
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook- r e: a. p8 R; i9 v
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in. r7 `. B( D0 M* h9 e' i* \
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so
# w% w( f6 P- s4 |+ A: q. k6 e) F4 Zhe chose not to push himself too hard and to conserve his energy for later. d- g7 s# L6 v$ P. E
events (whether this conforms to the Olympic spirit and the ‘use one’s
5 q; w% u$ L2 m3 Q* F, m6 @1 r1 Qbest efforts to win a match’ requirement that the Badminton World
) |& o/ ?/ `/ rFederation recently invoked to disqualify four badminton pairs is another9 h* f1 m% j4 I% @. d5 {
topic worth discussing, though probably not in Nature). Ye, on the other
/ Z6 y: F4 ^7 R0 X3 khand, was trailing behind after the first 300 metres and relied on freestyle
4 `/ ]" Y7 Q0 j, in which she has an edge, to win the race. Failing to mention this
& Z) \: [# d/ z& Z$ F2 }strategic difference, as well as the fact that Lochte is 23.25 seconds+ e; G8 U* v3 C& u) S) T' w
faster (4:05.18) than Ye overall, creates the illusion that a woman swam1 C) X5 ^5 P- _( O6 p
faster than the best man in the same sport, which sounds impossible. Putting! ]/ k/ m) ~/ g# J0 |8 j* \& x o& R
aside the gender argument, I believe this is still a leading question that4 n* M) {: Q/ {$ V ~ _/ L
implies to the reader that there is something fishy going on.
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0 d& o0 l0 ~; J( m/ EFourth is another example of cherry-picking. In the same event, there are- Y* A& }5 J' b- a3 G( \: g
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93( r( F' T( N' L0 [; G+ A6 I& t
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s% i4 S5 E. [) U$ _
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
* k8 }. M7 C- T3 _* x3 t# }! Lout, if we are just talking about the last 50 metres in a 400-metre IM,
) ^0 Z. q2 Q+ x4 R/ PLochter is not the example I would have used if I were the author. What kind
4 u! b3 ^3 }0 P4 }" Pof scientific rigorousness is Callaway trying to demonstrate here? Is it
* d, v4 w& Q. s, Q( ^logical that if Lochter is the champion, we should assume that he leads in
! h7 [) \3 [) i9 W+ }% a% uevery split? That would be a terrible way to teach the public how science6 m$ o1 Z( Y( ^7 \
works.4 E2 x! i5 f/ x& B r5 }
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and! U+ v. X9 z/ m9 D6 e
implies that a drug test cannot rule out the possibility of doping. Is this1 ~8 E, R" M( Z# i! o5 B
kind of agnosticism what Nature really wants to teach its readers? By that" i/ ^! @' w! u2 n1 J
standard, I estimate that at least half of the peer-reviewed scientific
' g* ?# K1 `7 vpapers in Nature should be retracted. How can one convince the editors and
" B9 U' ~5 l0 O" v) `# T- ]reviewers that their proposed theory works for every possible case? One
* `2 u& F, V6 B" Y* G Hcannot. One chooses to apply the theory to typical examples and to
, P4 Q8 t0 z) {& x; sdemonstrate that in (hopefully) all scenarios considered, the theory works
- @/ g: T2 u- l2 Z0 ito a degree, and that that should warrant publication until a counterexample
1 ^& n9 Q: O& Ais found. I could imagine that Callaway has a sceptical mind, which is
1 d; ^8 f$ m+ Qcrucial to scientific thinking, but that would be put to better use if he
) [8 i5 a# ]" s4 j( s9 ~wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
2 F9 E% L" |0 R- h* v( Cadvanced, non-detectable drug that the Chinese have come up with in the
$ F( c! J8 r# y9 j7 N. Z' |) B2 xpast 4 years (they obviously did not have it in Beijing, otherwise why not" I2 g$ N- A+ j- y# ]
use it and woo the audience at home?), based on data and rational derivation
8 U8 Q; [) P: A9 X# i+ h* s4 V! k+ [. This article, however, can be interpreted as saying that all athletes are0 G5 ^: G6 q0 V i$ Q; @4 j
doping and the authorities are just not good enough to catch them. That may
% L- n$ a r( F e, rbe true, logically, but definitely will not make the case if there is ever a) u( ], R; c: f
hearing by the governing body for water sports, FINA, to determine if Ye* ~' ?3 \, R5 V; w
has doped. To ask whether it is possible to obtain a false negative in a
& r5 |: g3 d t5 B! {$ K, q, Qdrug test looks like a rigged question to me. Of course it is possible:7 z2 v5 n) ^, G+ f1 }6 L; G7 S+ i
other than the athlete taking a drug that the test is not designed to detect
' k+ E! b9 a& y6 S8 T, o, anyone who has taken quantum 101 will tell you that everything is
9 p, n% Y& h! R/ o9 Rprobabilistic in nature, and so there is a probability that the drug in an! L6 _7 V; q1 \* Y/ V, H
athlete’s system could tunnel out right at the moment of the test. A slight) L+ s0 _: {! s* f, m
chance it may be, but should we disregard all test results because of it?/ ^* u! i: ]- N/ E2 B' u
Let’s be practical and reasonable, and accept that the World Anti-Doping: N0 T E ~ m3 t ]
agency (WADA) is competent at its job. Ye’s urine sample will be stored for8 K8 t5 y5 ~3 ?& k
eight years after the contest for future testing as technology advances.; I/ |% O# |' b# z
Innocent until proven guilty, shouldn’t it be?
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Sixth, and the last point I would like to make, is that the out-of-
% v' r- D2 v* Qcompetition drug test is already in effect, which Callaway failed to mention
/ K7 }# G8 y) v" t2 J. As noted in the president of WADA’s press release, drug testing for- l0 m) D- ~ u% P; ^
Olympians began at least six months before the opening of the London8 F" |7 l4 S `# \* J+ b4 W5 X
Olympics. Furthermore, 107 athletes have been banned from this Olympics for6 h% e- _1 f1 W0 X# W
doping. That may be the reason that “everyone will pass at the Olympic& W8 N9 W) l" D- U; Z" V" O9 q
games. Hardly anyone fails in competition testing” — those who did dope7 u1 y y* q) F2 U
have already been caught and sanctioned. Callaway is free to suggest that a
; K4 M, V1 K! S$ j& o; iplayer could have doped beforehand and fooled the test at the game, but this0 \8 T* m2 B, q5 j" J. z; U4 p
possibility is certainly ruled out for Ye.. U8 s7 h) H3 S) S4 ^2 {
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Over all, even though Callaway did not falsify any data, he did (
: C+ V9 W% N7 ~$ ~' J7 M& K3 lintentionally or not) cherry-pick data that, in my view, are far too
* I1 q/ ~1 _4 G2 ysuggestive to be fair and unbiased. If you want to cover a story of a
6 [! Z6 k2 @) ?' I3 p) hsuspected doping from a scientific point of view, be impartial and provide2 E1 f# f0 u& f% |+ d1 h& K5 |
all the facts for the reader to judge. You are entitled to your
& Z5 c' ^7 O/ N7 g% O- Einterpretation of the facts, and the expression thereof in your piece,
) ]* G; T6 `; j' `explicitly or otherwise, but showing only evidence that favours your
9 K' c7 Z& Q; A: Qargument is hardly good science or journalism. Such an article in a journal
2 u4 _7 Z% c O# psuch as Nature is not an appropriate example of how scientific research or2 z6 Y! m) W8 q, D
reporting should be done. |
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