Postdoctoral position in single molecule biophysics

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Postdoctoral fellow
University of Alberta and National Institute for Nanotechnology
; P4 u/ k1 a/ k, y& b7 k1 p& YEdmonton, Alberta, Canada
4 O0 j! n! T: jJob ID: 6926659
Job Duration: 1-2 Years
' h& y6 v' [! x% [# ^7 O- UPosition Title: Postdoctoral fellow
Required Travel: None
Min Education: Ph.D.
Posted: June 23, 2010
Job Function: Postdoc
Min Experience: None
# C' {+ y6 ~4 j/ iJob Type: Full-Time
Salary: Yearly Salary)
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Postdoctoral position in single molecule biophysics: protein folding and aggregation studies

# m% K0 E, r- Y# Q7 ~) g7 ?A postdoctoral position in single-molecule biophysics is available immediately at the Department of Physics, University of Alberta and the National Institute for Nanotechnology, in the research group of Michael Woodside. A talented experimentalist is sought to conduct research into protein folding, misfolding, and aggregation, primarily using single-molecule fluorescence techniques. The successful candidates will work with a team of technicians and other researchers (at the University, the Institute, and in industry) to characterize the folding and aggregation behaviour of various disease-related proteins and to explore the effects of potential drugs on the folding/misfolding. These studies will be done using fluorescence spectroscopies (e.g. FCS and FRET), optical tweezers, and standard biochemical approaches. Responsibilities will include designing experiments; operating, maintaining, and improving instrumentation (as needed); analyzing data and writing papers; and working with other team members to translate experimental results into methods for studying drug candidates.
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- z+ U2 ~+ V, `The National Institute for Nanotechnology is Canada’s flagship research institute in nanotechnology. It is located on the campus of the University of Alberta, in the provincial capital, Edmonton. A city of 1 million people, Edmonton has a lively cultural scene, and it also offers numerous opportunities for outdoors enthusiasts, especially in the unrivalled beauty of nearby Jasper and Banff national parks.

To apply, send a cover letter, curriculum vitae, and contact information (names, positions, phone numbers, mail and email addresses) for three references to Michael Woodside at michael.woodside@nrc-cnrc.gc.ca.

Job Requirements

; \3 t' S* _8 I. _" O/ X# `Motivated candidates with an interest in interdisciplinary research should have received a Ph.D. in physics, chemistry, biochemistry, biology or a closely related field within the last 2-3 years. Candidates should demonstrate a strong experimental record, with experience in single-molecule biophysics, fluorescence spectroscopy, force spectroscopy, laser optics, or protein folding, and should have a desire to learn and apply new techniques. Prior experience with single-molecule fluorescence methods would be particularly valued. Experience in molecular biology is helpful but not required, as technical support will be available in a fully-equipped biochemistry lab. The position is expected to last for at least 2 years.

1 X" N) d: F9 O0 u2 b0 V6 vContact Person: Michael Woodside
- Z  T% M; ^/ U5 Q7 ]Email Address: michael.woodside@nrc-cnrc.gc.ca
Phone: 780-641-1695
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Employment Opportunity / City of Edmonton Community Services
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