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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
2 a$ l( n u/ C1 \) P& ^, A如果是中国长大的,英语能到这种程度真是很不简单。- U3 Z7 r' R. V. e. K) J
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself& _9 J. h' d* {1 c
, regard as one of the most prestigious and influential physical-science- p2 I# N' F* G- ~" z
magazines — publish a thinly veiled biased article like this. Granted, this
5 a# J, e$ ^# M# P3 j. P2 uis not a peer-reviewed scientific article and did not go through the
! A& z x4 o2 p3 hscrutiny of picking referees. But to serve as a channel for the general; y. j6 m2 u0 I
populace to be in touch with and appreciate science, the authors and editors
) N: j( o6 t& A+ nshould at least present the readers with facts within the proper context,, z8 q- L! z0 Y! i) {" P: J, h
which they blatantly failed to do.7 X8 i6 z' [( b8 h
0 C; k$ `6 h' @/ K' C6 b4 f2 `First, to identify Ye’s performance increase, Ewen Callaway compared her
* \9 @, Q: Y: G( I0 L v% H/ L/ BOlympic 400-metre IM time with her performance at the World Championships in
7 N, `" C O4 Y2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
8 w) V& q4 ]5 n) }( [% p# K/ t, _& L7 Lanomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
I d- \. Q8 d8 @9 e6 g0 xpersonal best was 4:33.79 at the Asian Games in 2010. This leads to an* L" Z# Y6 u$ }% i( i2 O# j
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
& I# z* C% U. a4 Ndifference between the gold and silver medal, I see no reason for 5.38 s to# |9 l4 G3 w8 c4 A2 \9 b/ A3 m8 w7 q
be treated as 7 s.9 k6 _% B2 t1 T% L; T# w9 V4 K
8 x, U4 v3 j* F- BSecond, as previously pointed out, Ye is only 16 years old and her body is
: h9 V# k2 V& l0 A. t# u1 I3 }still developing. Bettering oneself by 5 seconds over two years may seem
$ i( P4 N: |# J- H1 [# ]impossible for an adult swimmer, but it certainly happens among youngsters.3 x- K8 i% ?) b% L! R; L* Y
An interview with Australian gold medallist Ian Thorpe revealed that his 400& I. j4 [! J. K
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.0 e4 o2 c% y3 H' d# E0 J
For regular people, including Callaway, it may be hard to imagine what an) f# f( N: Z! `
elite swimmer can achieve as he or she matures and undergoes scientific and
% u: T2 y# V* T' H& k& C9 T3 X! qpersistent training. But jumping to the conclusion that it is “anomalous”
& t4 | s9 j& {% n3 v; Zbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
" |) D9 V5 Y6 n4 @; cexample of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
. p0 ^) f& L$ W& ?: I6 G" H$ Othe last 50 metres, but Lochte had a huge lead in the first 300 metres, so: |- b& `8 i9 t
he chose not to push himself too hard and to conserve his energy for later$ g: m3 e+ w3 f0 T/ g
events (whether this conforms to the Olympic spirit and the ‘use one’s/ V! `& `! A" o6 E
best efforts to win a match’ requirement that the Badminton World
& s* _0 C9 h* y& k+ P* [0 [2 |Federation recently invoked to disqualify four badminton pairs is another5 {5 D2 {- e9 I
topic worth discussing, though probably not in Nature). Ye, on the other
) p, X6 g+ ~9 w9 W) r+ khand, was trailing behind after the first 300 metres and relied on freestyle7 {1 X; c0 ^; ^% Y
, in which she has an edge, to win the race. Failing to mention this
/ v/ w. i7 o' V6 Q p0 f# @3 e5 estrategic difference, as well as the fact that Lochte is 23.25 seconds& W0 G1 X$ R$ A& G
faster (4:05.18) than Ye overall, creates the illusion that a woman swam
2 S+ v* L7 d. J1 Wfaster than the best man in the same sport, which sounds impossible. Putting; i0 i$ _- o+ F
aside the gender argument, I believe this is still a leading question that, e& s/ @; v2 k$ L* E
implies to the reader that there is something fishy going on.
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, C9 s3 W1 M# x+ {$ MFourth is another example of cherry-picking. In the same event, there are/ H: ^/ B, }9 ?% D
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93' p. l/ `" Y; R$ E
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s" r& [, Y8 Z8 @# h+ h; x
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns6 o- [7 T6 P' q. q( l# ]! D. R
out, if we are just talking about the last 50 metres in a 400-metre IM,
: }( z! H. m& p( T, g1 K' ALochter is not the example I would have used if I were the author. What kind
6 G9 Q2 k( L- g* e) \4 L4 O E2 V4 w0 Kof scientific rigorousness is Callaway trying to demonstrate here? Is it: O, B2 v! E) c7 K. G+ ~. B* n
logical that if Lochter is the champion, we should assume that he leads in* I/ C: Q# {1 A; z
every split? That would be a terrible way to teach the public how science- d6 S3 k* [/ M
works.- p( S3 a+ Q) Y; i+ X) Y9 `* `
% l6 J M9 `! \+ w2 NFifth is the issue I oppose the most. Callaway quotes Ross Tucker and+ J T1 _8 i/ l5 j0 q
implies that a drug test cannot rule out the possibility of doping. Is this
* G- {" [3 G% ?% r7 ?3 t7 Q' {kind of agnosticism what Nature really wants to teach its readers? By that
+ E7 m. x7 m2 @5 L2 Bstandard, I estimate that at least half of the peer-reviewed scientific$ c2 n2 z9 J. ~* t, u
papers in Nature should be retracted. How can one convince the editors and
, `3 O0 x* r& f& y' `3 \0 Nreviewers that their proposed theory works for every possible case? One
0 S6 J+ O4 o3 Y* P! ]$ {' Kcannot. One chooses to apply the theory to typical examples and to3 t, X, [$ @7 \) v. X! K4 c
demonstrate that in (hopefully) all scenarios considered, the theory works
. Q e6 u: R: w3 T9 N0 I" A' xto a degree, and that that should warrant publication until a counterexample
7 J% E! V4 i) N8 k8 F7 ~+ i% J8 Tis found. I could imagine that Callaway has a sceptical mind, which is# b" e+ W, }( c
crucial to scientific thinking, but that would be put to better use if he$ `, D1 ]4 H @9 w5 p/ C8 R; [! d
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
8 z+ h/ W) N! g, C& Tadvanced, non-detectable drug that the Chinese have come up with in the
, H( N, v* N6 b/ q. }0 |past 4 years (they obviously did not have it in Beijing, otherwise why not
7 L! s: _9 Y* v( A ruse it and woo the audience at home?), based on data and rational derivation1 {4 f- y0 o6 j4 R! b, b
. This article, however, can be interpreted as saying that all athletes are" }, O/ O* i, h
doping and the authorities are just not good enough to catch them. That may
7 ~/ K9 J! D/ o4 U0 G1 G. D+ _be true, logically, but definitely will not make the case if there is ever a4 M! T }# ~/ S
hearing by the governing body for water sports, FINA, to determine if Ye0 P2 k2 v# F5 X, E+ i: q5 r
has doped. To ask whether it is possible to obtain a false negative in a
7 i3 M0 ~6 a* e' [! j5 ydrug test looks like a rigged question to me. Of course it is possible:# \2 ~9 @, L5 v" h1 a
other than the athlete taking a drug that the test is not designed to detect
: ~8 g& }4 }) H) C/ Y* [, anyone who has taken quantum 101 will tell you that everything is
5 b! x, G4 c8 w! a$ F8 uprobabilistic in nature, and so there is a probability that the drug in an0 j, k# A& m( X5 P2 o$ t( ~
athlete’s system could tunnel out right at the moment of the test. A slight
: e1 {" S0 u. ^. Y, Z% b) ]chance it may be, but should we disregard all test results because of it?
9 y% J; |3 Y& PLet’s be practical and reasonable, and accept that the World Anti-Doping
7 s% X" w" t& I6 g) P- m/ Iagency (WADA) is competent at its job. Ye’s urine sample will be stored for
3 i7 K/ p/ E6 T+ ^" K# w" X ieight years after the contest for future testing as technology advances.1 x; w8 J* v) k( x2 e+ Z. I8 t
Innocent until proven guilty, shouldn’t it be?
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6 O4 y0 _, V L( K: P, ESixth, and the last point I would like to make, is that the out-of-
. w; e; ~4 `; ^( m; |! T t' j! Wcompetition drug test is already in effect, which Callaway failed to mention
4 G, ?7 W( A, {. k+ Z) U! k. As noted in the president of WADA’s press release, drug testing for
9 r" F3 @; e7 F5 JOlympians began at least six months before the opening of the London
' L" e) u6 ^; L5 O7 v. \Olympics. Furthermore, 107 athletes have been banned from this Olympics for
( ]5 Z# G Z1 G1 y3 O1 tdoping. That may be the reason that “everyone will pass at the Olympic5 D6 n+ k, ^! i3 t8 p7 X4 P
games. Hardly anyone fails in competition testing” — those who did dope( ^. a1 U+ J9 p3 e
have already been caught and sanctioned. Callaway is free to suggest that a' M+ Q$ w; G- G. \: u9 Y7 W5 E( _
player could have doped beforehand and fooled the test at the game, but this6 _5 R1 l& I9 p$ f K
possibility is certainly ruled out for Ye.
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$ y6 W5 W( o3 F: k/ _Over all, even though Callaway did not falsify any data, he did (' m/ U5 h( B6 K% ]
intentionally or not) cherry-pick data that, in my view, are far too
/ w% K% o5 W, }7 B# p5 \9 Hsuggestive to be fair and unbiased. If you want to cover a story of a' a4 u; H9 R6 F+ H7 \
suspected doping from a scientific point of view, be impartial and provide
: ]4 @! c* o# i% x: j$ ]all the facts for the reader to judge. You are entitled to your
2 _5 q; P3 v4 F0 s1 U2 F5 J& k8 Tinterpretation of the facts, and the expression thereof in your piece,
/ n% Y! Q2 w J1 ]: O' r" W, Fexplicitly or otherwise, but showing only evidence that favours your, w9 l& Q3 e7 n5 K% {
argument is hardly good science or journalism. Such an article in a journal
1 F3 X3 S$ [3 ~* |2 ^: \1 usuch as Nature is not an appropriate example of how scientific research or
( ^9 r8 u* f, Z4 [$ }& @* J6 {reporting should be done. |
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