Post Doc: Protein profiling for chemical toxicity characterization

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Contact Name: Dorothy Carr
Contact Email: ordpostdocapps@epa.gov
Contact Telephone: (800) 433-9633
/ w* Q* a& s  n; H# TEmployer: U.S. EPA - Gulf Ecology Division
% h( X  V" {3 `% _- LBusiness Type: Government Laboratory
& Y& i7 w, a6 }% v8 X1 M5 ~' cJob Type: Research Scientist
1 h/ V4 j. K! S, NRegion: US
Location: Gulf Breeze, FL
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Employer: U.S. EPA - Gulf Ecology Division

; B* F% _" e' l% \; FBackground
+ q: D' p9 Q7 e2 F1 p. OWe are seeking a post-doctoral candidate with expertise in protein identification and mass spectrometry to participate in an ongoing research plan examining protein profiling and biomarker identification in small fish models as a means for chemical toxicity characterization.

3 k9 _" e' {7 m3 K1 XOur research is focused on the application of molecular techniques to link chemical mode of action (MOA) specific protein expression patterns to common toxicity endpoints, identify protein biomarkers associated with chemical pathway specific toxicity, develop in vitro diagnostic models for classifying chemicals by their protein signatures and determining if multivariate protein expression models can delineate multiple chemical MOAs associated with exposure to chemical mixtures. Research products from these studies will provide information necessary to distinguish biologically relevant changes in key toxicity pathways for use in the chemical hazard evaluation process.

The successful applicant should be interested in integrating their work within a collaborative, multidisciplinary research environment to address Agency-driven environmental research objectives.

Qualifications
. Q9 n$ t" \$ ?6 E) G* bThe preferred candidate will have demonstrated expertise in protein/peptide chemistry and biochemistry especially as related to protein detection using mass spectrometry, HPLC separation, or protein/peptide identification.

/ |" c/ K4 x2 w% x  l7 U9 eAdditional Notes
  X, N, d6 V& h9 T  jThe position is open for application from February 4, 2010 until February 26, 2010.
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Please see announcement and application instructions at
. f. t# C- o2 @+ H  M0 `http://cfpub.epa.gov/nheerl/inde ... docs.main#positions
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Contact Information:
/ c* ]# U/ ]: F' ?" s2 C- Z! JEmail your application materials to ordpostdocapps@epa.gov:
. Q6 `+ c: S+ U: g$ Y/ jInclude "NHEERL Post-Doctoral Program" in the subject line. Applications sent via email must be submitted in a format readable by this office, such as MS Word, portable document format (PDF), rich text format (RTF), or plain text. Use of any format we cannot read may invalidate your application.
$ a1 i5 K% w- k0 P+ I- Y3 R3 XNote - online applications from journal websites will not be accepted.

OR
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Mail your application materials to:
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US EPA, HRMD-C639-02
Attn: Ms. Dorothy Carr, NHEERL Post Doctoral Program
Research Triangle Park, NC 27711

8 K9 E" X. R% `# H, vOR
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- b& L+ g1 B9 cFax your application to +1 919 541 0160.

4 \, b( L2 b' ]! Z3 jIf you have questions, contact Ms. Dorothy Carr at (800) 433-9633 or via email to ordpostdocapps@epa.gov
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5 f0 ~; i) r" DU.S. EPA is an Equal Opportunity Employer and Provides Reasonable Accommodations to Applicants with Disabilities
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1 V4 T; T% v) \- oEmployment Opportunity / City of Edmonton Community Services
TO APPLY Online & further details, visit: PostDocJob.com.cn
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